Editorial
S1 Introduction.
Di Lorenzo, Carlo *; Winter, Harland S. +

 

Article
S2 Changing the Paradigm: New Directions in Federal Oversight of Human Research.
Koski, Greg Abstract
 
 
S7 Overview of Pediatric Gastroesophageal Reflux Disease and Proton Pump Inhibitor Therapy.
Colletti, Richard B. *; Di Lorenzo, Carlo + Abstract
 
 
S12 Acid Secretion From Birth to Adulthood.
Boyle, John T. Abstract
 
 
S17 The Role of Lower Esophageal Sphincter Function and Dysmotility in Gastroesophageal Reflux in Premature Infants and in the First Year of Life.
Davidson, Geoffrey Abstract
 
 
S23 Eosinophilic Esophagitis in Children and Adults.
Liacouras, Chris A. Abstract
S29 Tests to Assess Symptoms of Gastroesophageal Reflux in Infants and Children.
Orenstein, Susan R. Abstract
S33 Outcomes of Pediatric Gastroesophageal Reflux Disease: In the First Year of Life, in Childhood, and in Adults . . . Oh, and Should We Really Leave Helicobacter pylori Alone?
Gold, Benjamin D. Abstract
 
 
S40 Current Regulatory Policies Regarding Pediatric Indications and Exclusivity.
Rodriguez, William J.; Roberts, Rosemary; Murphy, Dianne Abstract
 
 
S46 Efficacy and Safety Measurements of Proton Pump Inhibitors in Infants and Children.
James, Laura P. Abstract
S52 Proton Pump Inhibitors in Pediatrics: Relevant Pharmacokinetics and Pharmacodynamics.
Kearns, Gregory L. *; Winter, Harland S. + Abstract
 
 
S60 Are Proton Pump Inhibitors Indicated for the Treatment of Gastroesophageal Reflux in Infants and Children?
Rudolph, Colin D. Abstract

 

Rapporteur Team I Summary
S65 Do Children With Gastroesophageal Reflux Become Adults With Gastroesophageal Reflux? What Is the Role of Acid Suppression in Children?
Boyle, John T. (Team Leader); Co, John; Davidson, Geoffrey; Freston, James; Nelson, Suzanne; Tolia, Vasundhara; Werlin, Steven L.; Others

 

Rapporteur Team II Summary
S69 What Safety Data Are Needed for a Medication to Treat Gastroesophageal Reflux in Premature Infants? In Children Younger Than 1 Year of Age? How to Design a Long-Term Safety Registry for Children?
Blumer, Jeffrey L. (Team Leader); Heyman, Melvin B.; Vandenplas, Yvan; Ward, Robert M.

 

Rapporteur Team III Summary
S72 What Outcome Measures Are Needed to Assess Gastroesophageal Reflux Disease in Children? What Study Design Is Appropriate? What New Knowledge Is Needed?
Gold, Benjamin D. (Team Leader); Co, John; Colletti, Richard B.; Euler, Arthur R.; Ferris, Timothy G.; Fitzgerald, Joseph F.; Flores, Alejandro F.; Gallo-Torres, Hugo; Orenstein, Susan R.; Rodriguez, William J.; Willging, Paul